Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.58 |
| ▸ | AR | P10275 | 3/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | TNIK | Q9UKE5 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16429066 | 0.85 | PTGDR2 (0.60) | KDM1AARPTGDR2MAOAMAOB | |
| SCHEMBL29788111 | 0.85 | PTGDR2 (0.60) | KDM1AARPTGDR2MAOAMAOB | |
| SCHEMBL11616908 | 0.84 | KDM1A (0.56) | KDM1AARPTGDR2PLAUTNIK | |
| SCHEMBL13370824 | 0.82 | KDM1A (0.60) | KDM1AARPTGDR2MAOAMAOB | |
| SCHEMBL21180018 | 0.80 | KDM1A (0.58) | KDM1AARPTGDR2MAOAMAOB | |
| SCHEMBL21599450 | 0.80 | KDM1A (0.58) | KDM1AARPTGDR2MAOAMAOB | |
| SCHEMBL16894230 | 0.78 | KDM1A (0.56) | KDM1AARPTGDR2PLAUNR3C2 | |
| SCHEMBL2753744 | 0.77 | CA12 (0.50) | — | |
| SCHEMBL20924264 | 0.77 | KDM1A (0.70) | KDM1AARPTGDR2MAOAMAOB | |
| SCHEMBL2037082 | 0.77 | KDM1A (0.55) | KDM1APTGDR2CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |