SCHEMBL5328014

SCHEMBL5328014

CCC=C(N)C(=CCC)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 1/20 0.39
GRIK2 Q13002 1/20 0.39
EP300 Q09472 1/20 0.39
LDHA P00338 1/20 0.30
LDHB P07195 1/20 0.30
GABRR1 P24046 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1135184 0.83 GRIK1 (0.41) GRIK1GRIK2EP300LDHALDHB
SCHEMBL27985112 0.83 GRIK1 (0.41) GRIK1GRIK2EP300LDHALDHB
SCHEMBL692111 0.82
SCHEMBL16130542 0.82
SCHEMBL1284208 0.82
SCHEMBL190066 0.82 EP300 (0.52) GRIK1GRIK2EP300GABRR1
SCHEMBL29210205 0.82 EP300 (0.46) GRIK1GRIK2EP300GABRR1
SCHEMBL20598292 0.80
Chloromethane SCHEMBL7216942 0.78 GRIK1 (0.41) GRIK1GRIK2EP300LDHALDHB
Butane SCHEMBL4623691 0.78 GRIK1 (0.41) GRIK1GRIK2EP300LDHALDHB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007142804-A2 PREPARATION OF COMPLEXING AGENTS AND METAL ION COMPLEXES IN AQUEOUS MEDIA MALLINCKRODT INC. (US) 2007-12-13 WO disclosed