Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 20/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4867347 | 1.00 | MPL (0.79) | MPL | |
| SCHEMBL4879489 | 0.93 | MPL (0.80) | MPL | |
| SCHEMBL4877554 | 0.88 | MPL (1.00) | MPL | |
| SCHEMBL4879501 | 0.88 | MPL (0.84) | MPL | |
| SCHEMBL4877617 | 0.88 | MPL (0.79) | MPL | |
| SCHEMBL4873040 | 0.87 | MPL (0.91) | MPL | |
| SCHEMBL4879557 | 0.86 | MPL (0.76) | MPL | |
| SCHEMBL4877658 | 0.86 | MPL (0.76) | MPL | |
| SCHEMBL4877641 | 0.86 | MPL (0.76) | MPL | |
| SCHEMBL4877839 | 0.85 | MPL (0.80) | MPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1794156-A2 | TROMBOPOIETIN RECEPTOR AGONISTS | Pfizer Products Incorporated (US) | 2007-06-13 | — | — | EP | claimed |
| WO-2006033005-A2 | THROMBOPOIETIN RECEPTOR AGONISTS | PFIZER PRODUCTS INC. (US) | 2006-03-30 | — | — | WO | claimed |