Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23263850 | 0.79 | HDAC4 (0.46) | KDM1ARAB9ASMN1; SMN2MAPTDHODH | |
| SCHEMBL31114208 | 0.77 | CYP11B1 (0.47) | KDM1AIDO1MEN1KMT2ARAB9A | |
| SCHEMBL27795031 | 0.77 | KDM1A (0.51) | KDM1AIDO1MEN1KMT2ARAB9A | |
| SCHEMBL27876969 | 0.77 | KDM1A (0.51) | KDM1AIDO1MEN1KMT2ANPC1 | |
| SCHEMBL16627983 | 0.77 | CCR1 (0.56) | KDM1AIDO1MEN1KMT2ARAB9A | |
| SCHEMBL28690289 | 0.77 | MAP4K4 (0.44) | RAB9ANPC1SMN1; SMN2ATMDHODH | |
| SCHEMBL15851441 | 0.77 | IDO1 (0.46) | IDO1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL4337886 | 0.77 | IDO1 (0.46) | IDO1MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL21661952 | 0.77 | KDM1A (0.51) | KDM1AIDO1MEN1KMT2ARAB9A | |
| SCHEMBL14988677 | 0.77 | KDM1A (0.59) | KDM1AIDO1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105315319-B | Hepatitis C virus inhibitor and application thereof | 南京圣和药业股份有限公司 | 2020-11-20 | — | — | CN | disclosed |
| CN-106488910-A | Inhibitors of kras g12c | 亚瑞克西斯制药公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-102482259-B | Pyrrolidine derivatives as nk3 receptor antagonists | HOFFMANN LA ROCHE | 2014-09-17 | — | — | CN | disclosed |
| CN-102482259-A | PYRROLIDINE DERIVATIVES AS NK3 RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE | 2012-05-30 | — | — | CN | disclosed |
| CN-102227428-A | Arylcyclohexylethers of dihydrotetraazabenzoazulenes for use as vasopressin via receptor antagonists | HOFFMANN LA ROCHE | 2011-10-26 | — | — | CN | disclosed |
| CN-1993328-B | Quinoline derivative and insecticide containing same as active constituent | MEIJI SEIKA KAISHA | 2010-12-22 | — | — | CN | disclosed |
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| CN-1993328-A | Quinoline derivative and insecticide containing same as active constituent | MEIJI SEIKA KAISHA (JP) | 2007-07-04 | — | — | CN | disclosed |
| CN-1589271-A | Fused heterocyclic succinimide compounds and analogs thereof as modulators of nuclear hormone receptor function | BRISTOL MYERS SQUIBB CO (US) | 2005-03-02 | — | — | CN | disclosed |