Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.52 |
| ▸ | CCR5 | P51681 | 2/20 | 0.52 |
| ▸ | CCR8 | P51685 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 2/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | METAP1 | P53582 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990815 | 0.87 | CYP19A1 (0.56) | CCR1CCR5CCR8ALDH1A1NPC1 | |
| SCHEMBL30090507 | 0.87 | CYP19A1 (0.56) | CCR1CCR5CCR8ALDH1A1NPC1 | |
| SCHEMBL2322004 | 0.83 | NPC1 (0.69) | CCR1CCR5CCR8ALDH1A1NPC1 | |
| SCHEMBL30900828 | 0.81 | KDM1A (0.54) | CCR1CCR5CCR8ALDH1A1NPC1 | |
| SCHEMBL6068182 | 0.81 | KDM1A (0.54) | CCR1CCR5CCR8ALDH1A1NPC1 | |
| SCHEMBL29865517 | 0.80 | KDM4E (0.54) | CCR1CCR5CCR8ALDH1A1NPC1 | |
| SCHEMBL15485572 | 0.80 | KDM4E (0.54) | CCR1CCR5CCR8ALDH1A1NPC1 | |
| SCHEMBL20591288 | 0.80 | KDM4E (0.54) | CCR1CCR5CCR8ALDH1A1NPC1 | |
| SCHEMBL25299620 | 0.80 | CCR1 (0.55) | CCR1CCR5CCR8ALDH1A1NPC1 | |
| SCHEMBL16385311 | 0.80 | NPC1 (0.47) | CCR1CCR5CCR8ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |