Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328444 | 1.00 | SMN1; SMN2 (0.61) | SMN1; SMN2CA14CA12KMT2AMME | |
| SCHEMBL857610 | 0.85 | SMN1; SMN2 (0.75) | SMN1; SMN2CA14CA12KMT2ACA7 | |
| SCHEMBL857611 | 0.85 | SMN1; SMN2 (0.75) | SMN1; SMN2CA14CA12KMT2ACA7 | |
| SCHEMBL17124702 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2CA14CA12KMT2AMME | |
| SCHEMBL15015776 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2CA14CA12KMT2AMME | |
| SCHEMBL6446523 | 0.80 | SMN1; SMN2 (0.61) | SMN1; SMN2CA14CA12KMT2AMME | |
| SCHEMBL5512536 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2CA14CA12KMT2ACA7 | |
| SCHEMBL561667 | 0.76 | SMN1; SMN2 (0.60) | SMN1; SMN2CA14CA12KMT2ACA7 | |
| SCHEMBL11118030 | 0.76 | SMN1; SMN2 (0.88) | SMN1; SMN2CA14CA12KMT2AALDH1A1 | |
| SCHEMBL188811 | 0.76 | SMN1; SMN2 (0.70) | SMN1; SMN2CA14CA12KMT2ACA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007011910-A2 | CHIRAL AMINE-CATALYZED ASYMMETRIC ADDITION OF CARBON-CENTERED NUCLEOPHILES TO IMINES | TRUSTEES OF BOSTON UNIVERSITY (US) | 2007-01-25 | — | — | WO | disclosed |