SCHEMBL5328452 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	KDM4E	B2RXH2	1/20	0.33

▸	ALDH1A1	P00352	1/20	0.33

▸	HPGD	P15428	1/20	0.33

▸	HSD17B10	Q99714	1/20	0.33

▸	GUCY1B2	O75343	6/20	0.33

▸	GUCY1A2	P33402	6/20	0.33

▸	GUCY1A1	Q02108	6/20	0.33

▸	GUCY1B1	Q02153	6/20	0.33

▸	CTSA	P10619	1/20	0.32

▸	MAPT	P10636	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5324424	1.00	KDM4E (0.33)	KDM4EALDH1A1HPGDHSD17B10GUCY1B2
SCHEMBL5328449	1.00	KDM4E (0.33)	KDM4EALDH1A1HPGDHSD17B10GUCY1B2
SCHEMBL5330153	0.91	CYP3A4 (0.34)	CTSA
SCHEMBL5327758	0.91	CYP3A4 (0.34)	CTSA
SCHEMBL5327754	0.91	CYP3A4 (0.34)	CTSA
SCHEMBL5566372	0.87	PRKDC (0.34)	ALDH1A1MAPT
SCHEMBL4977432	0.87	PRKDC (0.34)	ALDH1A1MAPT
SCHEMBL5451120	0.87	PRKDC (0.34)	ALDH1A1MAPT
SCHEMBL5326673	0.85	AOC3 (0.32)	—
SCHEMBL5326656	0.85	AOC3 (0.32)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2007141253-A1	PROCESS FOR THE PRODUCTION OF INTERMEDIATES FOR THE PREPARATION OF TRICYCLIC IMIDAZOPYRIDINES	NYCOMED GMBH (DE)	2007-12-13	—	—	WO	claimed