Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 12/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532974 | 0.92 | EDNRA (0.49) | EDNRAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL3976730 | 0.85 | EDNRA (0.42) | EDNRAMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL3972434 | 0.83 | MAPT (0.49) | EDNRAMEN1KMT2AMAPTEDNRB | |
| SCHEMBL3975239 | 0.83 | EDNRA (0.46) | EDNRAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL532871 | 0.82 | MEN1 (0.45) | EDNRAMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL3976237 | 0.81 | MEN1 (0.44) | EDNRAMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL3977551 | 0.80 | MEN1 (0.48) | EDNRAMEN1KMT2ACYP3A4MAPT | |
| SCHEMBL3974388 | 0.79 | MAPT (0.49) | EDNRAMEN1KMT2AMAPTEDNRB | |
| SCHEMBL533012 | 0.79 | MEN1 (0.56) | EDNRAMEN1KMT2ACYP3A4TSHR | |
| SCHEMBL3978595 | 0.79 | MEN1 (0.46) | EDNRAMEN1KMT2ACYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415760-A2 | CCR-9 antagonists | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2012-02-08 | — | — | EP | disclosed |