Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 11/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328659 | 1.00 | PTH1R (0.43) | PTH1RMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL5319970 | 0.86 | PTH1R (0.43) | PTH1RMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL5319972 | 0.86 | PTH1R (0.43) | PTH1RMEN1KMT2APTGS1PTGS2 | |
| SCHEMBL5321548 | 0.86 | PTH1R (0.52) | PTH1RCCKBR | |
| SCHEMBL5320173 | 0.86 | PTH1R (0.52) | PTH1RCCKBR | |
| SCHEMBL5320208 | 0.86 | PTH1R (0.52) | PTH1RCCKBR | |
| SCHEMBL5325682 | 0.86 | PTH1R (0.52) | PTH1RCCKBR | |
| SCHEMBL5403042 | 0.83 | PTH1R (0.46) | PTH1RCCKBR | |
| SCHEMBL5403035 | 0.83 | PTH1R (0.46) | PTH1RCCKBR | |
| SCHEMBL5326089 | 0.80 | PTH1R (0.49) | PTH1RCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |