SCHEMBL5328680

SCHEMBL5328680

O=C(O)C(Cc1ccccc1)N(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPI P09923 1/20 0.52
PKM P14618 1/20 0.52
PTGS1 P23219 1/20 0.52
XIAP P98170 1/20 0.52
SLC7A5 Q01650 1/20 0.52
MDM2 Q00987 1/20 0.50
CYP1A2 P05177 1/20 0.50
ALDH1A1 P00352 1/20 0.45
MAPT P10636 1/20 0.45
CTRB1 P17538 1/20 0.45
CPA3 P15088 3/20 0.44
CPA1 P15085 2/20 0.44
FOLH1 Q04609 1/20 0.44
CPB1 P15086 1/20 0.44
CPB2 Q96IY4 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
SRR Q9GZT4 2/20 0.43
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28415387 0.90 SLC7A5 (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL28415388 0.90 SLC7A5 (0.51) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27296650 0.88 ALPI (0.47) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27296653 0.88 ALPI (0.47) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27480743 0.85 SLC7A5 (0.49) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL27480744 0.85 SLC7A5 (0.49) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL9754294 0.83 CYP1A2 (0.55) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL2943084 0.83 ALPI (0.49) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL2943085 0.83 ALPI (0.49) ALPIPKMPTGS1XIAPSLC7A5
SCHEMBL4107271 0.83 SLC7A5 (0.50) ALPIPKMPTGS1XIAPSLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853626-A2 AMYLOID-BINDING PEPTIDES, ANALOGUES AND USES THEREOF Senexis Limited (GB) 2007-11-14 EP disclosed
WO-2006087550-A2 AMYLOID-BINDING PEPTIDES, ANALOGUES AND USES THEREOF SENEXIS LIMITED (GB) 2006-08-24 WO disclosed