SCHEMBL532883

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL531893	0.91	PARP1 (0.66)	PARP1DRD4DRD2MEN1KMT2A
	SCHEMBL531734	0.90	PARP1 (0.79)	PARP1DRD4DRD2IKZF1HTR1A
	SCHEMBL531959	0.88	PARP1 (0.82)	PARP1DRD4DRD2KDM4EMAPT
	SCHEMBL532419	0.80	PARP1 (0.82)	PARP1MEN1KMT2A
	SCHEMBL532372	0.78	PARP1 (1.00)	PARP1DRD4DRD2DRD3
	SCHEMBL532326	0.78	PARP1 (1.00)	PARP1DRD4DRD2DRD3
	SCHEMBL532396	0.78	PARP1 (1.00)	PARP1DRD4DRD2DRD3
	SCHEMBL532509	0.78	PARP1 (0.77)	PARP1DRD4DRD2KDM4EMEN1
	SCHEMBL2122366	0.77	PARP1 (1.00)	PARP1DRD4DRD2KDM4EDRD3
	SCHEMBL2122722	0.73	PARP1 (0.82)	PARP1DRD4DRD2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.