Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 10/20 | 0.69 |
| ▸ | CCKBR | P32239 | 9/20 | 0.42 |
| ▸ | XIAP | P98170 | 1/20 | 0.41 |
| ▸ | CCKAR | P32238 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5329011 | 1.00 | PTH1R (0.69) | PTH1RCCKBRXIAPCCKAR | |
| SCHEMBL5324848 | 0.90 | PTH1R (0.74) | PTH1RCCKBRCCKAR | |
| SCHEMBL14566437 | 0.87 | PTH1R (0.69) | PTH1RCCKBRCCKAR | |
| SCHEMBL5322281 | 0.84 | PTH1R (0.70) | PTH1RCCKBRCCKAR | |
| SCHEMBL5329075 | 0.84 | PTH1R (0.59) | PTH1RCCKBRCCKAR | |
| SCHEMBL5325535 | 0.84 | PTH1R (0.66) | PTH1RCCKBRCCKAR | |
| SCHEMBL5323646 | 0.82 | PTH1R (0.67) | PTH1RCCKBRCCKAR | |
| SCHEMBL5363617 | 0.82 | PTH1R (0.63) | PTH1RCCKBR | |
| SCHEMBL5325329 | 0.82 | PTH1R (0.81) | PTH1RCCKBRCCKAR | |
| SCHEMBL5322722 | 0.82 | PTH1R (0.83) | PTH1RCCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |