SCHEMBL5329328

SCHEMBL5329328

FC(F)(F)c1nc(CI)cs1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 2/20 0.33
MCHR1 Q99705 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9045575 0.79 GFER (0.42) IDH1MCHR1
SCHEMBL12607354 0.79 IDH1 (0.33) IDH1MCHR1
SCHEMBL1999685 0.79 SRC (0.35) IDH1MCHR1
SCHEMBL5437866 0.79 IDH1 (0.36) IDH1MCHR1
SCHEMBL1569158 0.79 IDH1 (0.33) IDH1MCHR1
SCHEMBL9262966 0.79 MCHR1 (0.34) IDH1MCHR1
SCHEMBL127293 0.79 IDH1 (0.33) IDH1MCHR1
SCHEMBL10588675 0.76 TAAR1 (0.34) IDH1MCHR1
SCHEMBL17263328 0.76 CCR4 (0.40) IDH1MCHR1
SCHEMBL3694549 0.75 IDH1 (0.32) IDH1MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007145349-A2 SUBSTITUTED PYRROLE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-12-21 WO disclosed