SCHEMBL5329401

SCHEMBL5329401

O=C1C(=Cc2ccccc2)C=NN1c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.41
MEN1 O00255 7/20 0.41
L3MBTL1 Q9Y468 4/20 0.41
ITGA4 P13612 1/20 0.41
ITGB7 P26010 1/20 0.41
GAA P10253 3/20 0.40
KAT8 Q9H7Z6 1/20 0.40
MAPT P10636 6/20 0.39
ALDH1A1 P00352 5/20 0.39
TDP1 Q9NUW8 4/20 0.39
MAPK1 P28482 2/20 0.39
POLB P06746 2/20 0.39
LMNA P02545 1/20 0.39
HTT P42858 1/20 0.39
AKR1B1 P15121 1/20 0.36
KDM4E B2RXH2 3/20 0.36
EP300 Q09472 1/20 0.36
PKM P14618 1/20 0.35
HPGD P15428 1/20 0.35
RECQL P46063 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5329399 1.00 KMT2A (0.41) KMT2AMEN1L3MBTL1ITGA4ITGB7
SCHEMBL10786628 0.81 KDM4E (0.40) KMT2AMEN1L3MBTL1GAAMAPT
SCHEMBL10786638 0.81 KDM4E (0.40) KMT2AMEN1L3MBTL1GAAMAPT
SCHEMBL6735947 0.74 KMT2A (0.41) KMT2AMEN1L3MBTL1GAAMAPT
SCHEMBL10134037 0.71 KMT2A (0.39) KMT2AMEN1L3MBTL1GAAMAPT
SCHEMBL10035997 0.67 KMT2A (0.81) KMT2AMEN1L3MBTL1GAAKAT8
SCHEMBL28476008 0.67 KMT2A (0.81) KMT2AMEN1L3MBTL1GAAKAT8
SCHEMBL28967916 0.67 KMT2A (0.81) KMT2AMEN1L3MBTL1GAAKAT8
SCHEMBL28967912 0.66 MEN1 (0.71) KMT2AMEN1L3MBTL1GAAKAT8
SCHEMBL28967915 0.66 MEN1 (0.71) KMT2AMEN1L3MBTL1GAAKAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2007070433-A ORGANIC DYE USING PYRAZOLONE DERIVATIVE SHIPRO KASEI KAISHA LTD 2007-03-22 JP disclosed
JP-2007069421-A OPTICAL RECORDING MEDIUM SHIPRO KASEI KAISHA LTD 2007-03-22 JP disclosed