Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 12/20 | 0.35 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA2 | P00918 | 5/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328208 | 0.80 | CA1 (0.35) | P2RX4CA1CA2CA7CA13 | |
| SCHEMBL14513391 | 0.78 | CA1 (0.38) | P2RX4CA1CA2CA7CA13 | |
| Hydrochloric Acid SCHEMBL5360907 | 0.78 | CA1 (0.37) | P2RX4CA1CA2CA7CA13 | |
| SCHEMBL5577163 | 0.77 | CA1 (0.37) | P2RX4CA1CA2CA7CA13 | |
| SCHEMBL5576878 | 0.75 | CA12 (0.35) | P2RX4CA1CA2CA7CA13 | |
| SCHEMBL5310504 | 0.73 | NPC1 (0.37) | CA1CA2CA7CA13CA12 | |
| SCHEMBL5328513 | 0.70 | NPC1 (0.35) | CA1CA2CA7CA13CA12 | |
| SCHEMBL14513390 | 0.69 | SLC2A1 (0.46) | CA1CA2CA12CA5ACA9 | |
| SCHEMBL5329224 | 0.69 | SMN1; SMN2 (0.33) | P2RX4NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL5330503 | 0.69 | SLC2A1 (0.46) | CA1CA2CA12CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007052831-A1 | PREVENTIVES/REMEDIES FOR URINARY DISTURBANCE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-05-10 | — | — | WO | disclosed |
| WO-2007033032-A1 | CYCLOPROPYL FUSED INDOLOBENZAZEPINE HCV NS5B INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-03-22 | — | — | WO | disclosed |