Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945086 | 0.94 | RPS6KA3 (0.40) | SRD5A2RPS6KA3DRD2ADRA1DHTR2A | |
| SCHEMBL3943354 | 0.92 | SRD5A2 (0.48) | SRD5A2SRD5A1FGFR1 | |
| SCHEMBL241854 | 0.87 | SRD5A2 (0.39) | SRD5A2SRD5A1 | |
| SCHEMBL841837 | 0.79 | RPS6KA3 (0.41) | RPS6KA3PLAUBCAT2ROCK2PIM1 | |
| SCHEMBL50820 | 0.74 | RPS6KA3 (0.49) | RPS6KA3PLAUPLA2G10BCAT2ROCK2 | |
| SCHEMBL50474 | 0.74 | RPS6KA3 (0.39) | RPS6KA3PLAUROCK2PIM1PIM3 | |
| SCHEMBL3244153 | 0.72 | SRD5A2 (0.43) | SRD5A2SRD5A1FGFR1 | |
| SCHEMBL3088133 | 0.70 | RPS6KA3 (0.54) | RPS6KA3HTR2AHTR2CBCAT2RPS6KA2 | |
| SCHEMBL3941964 | 0.70 | RPS6KA3 (0.43) | RPS6KA3PLAUPLA2G10ROCK2PIM1 | |
| SCHEMBL4822220 | 0.68 | RPS6KA3 (0.40) | RPS6KA3PLAUROCK2PIM1PIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007033175-A1 | INDOLOBENZAZEPINE HCV NS5B INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-03-22 | — | — | WO | disclosed |