Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322655 | 0.80 | KMT2A (0.59) | KMT2AMEN1TSHRMAPK10KDM4E | |
| SCHEMBL5330912 | 0.79 | PLA2G1B (0.61) | TSHRTACR1ALDH1A1POLB | |
| SCHEMBL7666895 | 0.79 | KMT2A (0.60) | KMT2AMEN1TSHRMAPK10KDM4E | |
| SCHEMBL14521458 | 0.78 | KMT2A (0.52) | KMT2AMEN1TSHRMAPK10KDM4E | |
| SCHEMBL18415450 | 0.77 | MEN1 (0.58) | KMT2AMEN1TSHRMAPK10KDM4E | |
| SCHEMBL12672610 | 0.76 | KMT2A (0.55) | KMT2AMEN1TSHRMAPK10KDM4E | |
| SCHEMBL31349283 | 0.76 | MEN1 (0.56) | KMT2AMEN1TSHRMAPK10KDM4E | |
| SCHEMBL5669243 | 0.76 | TSHR (0.59) | KMT2AMEN1TSHRMAPK10KDM4E | |
| SCHEMBL15338710 | 0.75 | KMT2A (0.50) | KMT2AMEN1TSHRMAPK10KDM4E | |
| SCHEMBL5328968 | 0.75 | MEN1 (0.50) | KMT2AMEN1TSHRMAPK10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142431-A1 | NEW NON-PEPTIDE COMPOUNDS, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (KR) | 2007-12-13 | — | — | WO | disclosed |