Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.56 |
| ▸ | CASP7 | P55210 | 2/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.49 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.48 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331673 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1MAPTRXFP1GAA | |
| SCHEMBL5330767 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1MAPTRXFP1GAA | |
| SCHEMBL5328894 | 0.87 | KDM4E (0.81) | KDM4EALDH1A1MAPTRXFP1GAA | |
| SCHEMBL5330769 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1MAPTRXFP1GAA | |
| SCHEMBL5328883 | 0.85 | RXFP1 (0.70) | KDM4EALDH1A1MAPTRXFP1GAA | |
| SCHEMBL5328500 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1MAPTRXFP1GAA | |
| SCHEMBL5334050 | 0.80 | BRD4 (0.61) | KDM4EALDH1A1MAPTHSD17B10PTGDR2 | |
| SCHEMBL5328637 | 0.80 | KDM4E (0.62) | KDM4EALDH1A1MAPTRXFP1GAA | |
| SCHEMBL5324274 | 0.78 | KDM4E (0.60) | KDM4EALDH1A1MAPTRXFP1GAA | |
| SCHEMBL6583766 | 0.78 | KDM4E (0.77) | KDM4EALDH1A1MAPTRXFP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007144625-A1 | 2-OXO-2H-CHROMENE COMPOUNDS | ARGENTA DISCOVERY LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |