Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.37 |
| ▸ | SMC2 | O95347 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | SMC1A | Q14683 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | Q6ZSR9 | Q6ZSR9 | 1/20 | 0.37 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343797 | 0.84 | MAP2K1 (0.39) | L3MBTL1PTGS2MAP2K1SMC2EGFR | |
| SCHEMBL3974319 | 0.82 | SRC (0.39) | L3MBTL1PTGS2MAP2K1SMC2EGFR | |
| SCHEMBL3973788 | 0.79 | MAP2K1 (0.38) | L3MBTL1PTGS2MAP2K1SMC2EGFR | |
| SCHEMBL3979226 | 0.78 | SRC (0.38) | L3MBTL1PTGS2MAP2K1SMC2EGFR | |
| SCHEMBL13842074 | 0.78 | GAA (0.40) | L3MBTL1PTGS2MAP2K1SMC2EGFR | |
| SCHEMBL13842022 | 0.77 | MAP2K1 (0.45) | L3MBTL1MAP2K1SMC2EGFRCSNK2A2 | |
| SCHEMBL3974727 | 0.77 | GAA (0.37) | PTGS2MAP2K1SMC2EGFRCSNK2A2 | |
| SCHEMBL3978828 | 0.76 | CSF1R (0.43) | MAP2K1SMC2EGFRCSNK2A2MAP2K2 | |
| SCHEMBL1341369 | 0.76 | MAP2K1 (0.53) | L3MBTL1PTGS2MAP2K1SMC2EGFR | |
| SCHEMBL4239049 | 0.75 | MAP2K1 (0.47) | MAP2K1MAP2K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007022529-A2 | METHOD OF TREATING INFLAMMATORY DISEASES | ARRAY BIOPHARMA INC. (US) | 2007-02-22 | — | — | WO | disclosed |