Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL171869 | 0.77 | MEN1 (0.65) | MEN1TSHRKMT2A | |
| SCHEMBL15189362 | 0.77 | MEN1 (0.65) | MEN1TSHRKMT2A | |
| SCHEMBL578113 | 0.77 | MEN1 (0.65) | MEN1TSHRKMT2A | |
| SCHEMBL232820 | 0.77 | MEN1 (0.65) | MEN1TSHRKMT2A | |
| Water SCHEMBL8812670 | 0.76 | MEN1 (0.63) | MEN1TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL17255832 | 0.76 | MEN1 (0.63) | MEN1TSHRKMT2A | |
| SCHEMBL30819241 | 0.76 | MEN1 (1.00) | MEN1TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL15819856 | 0.76 | MEN1 (0.63) | MEN1TSHRKMT2A | |
| SCHEMBL1852325 | 0.76 | MEN1 (1.00) | MEN1TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL1340043 | 0.74 | MEN1 (0.96) | MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831208-A1 | QUATERNARY AMMONIUM SALTS AS M3 ANTAGONISTS | Novartis AG (CH) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006066929-A1 | QUATERNARY AMMONIUM SALTS AS M3 ANTAGONISTS | NOVARTIS AG (CH) | 2006-06-29 | — | — | WO | disclosed |