Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635990 | 0.86 | EPHX2 (0.61) | EPHX2NR1H4LTA4HPPARAPPARG | |
| SCHEMBL4913978 | 0.82 | EPHX2 (0.52) | SCN8AEPHX2NR1H4PPARAPPARG | |
| SCHEMBL19280078 | 0.80 | MEN1 (0.62) | SMN1; SMN2 | |
| SCHEMBL16269079 | 0.80 | MTOR (0.51) | SCN8AEPHX2PPARAPPARGNAMPT | |
| SCHEMBL3350274 | 0.80 | EPHX2 (0.46) | SCN8AEPHX2NR1H4LTA4HPPARA | |
| SCHEMBL8348550 | 0.79 | SCN8A (0.55) | SCN8AEPHX2NR1H4HTR2CPLA2G1B | |
| SCHEMBL16839848 | 0.78 | POLB (0.56) | SCN8AEPHX2NR1H4LTA4HPPARA | |
| SCHEMBL23607918 | 0.78 | KDM4E (0.59) | PLA2G1BATG4BCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL6122751 | 0.77 | SCN8A (0.54) | SCN8AEPHX2NR1H4HTR2CPLA2G1B | |
| SCHEMBL4656040 | 0.77 | SCN8A (0.59) | SCN8AEPHX2NR1H4HTR2CPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047432-A1 | SULFONAMIDE DERIVATIVES AS MODULATORS OF PPAR | KALYPSYS, INC. (US) | 2007-04-26 | — | — | WO | disclosed |