SCHEMBL5331015

SCHEMBL5331015

CC1(C)O[C@@H](CO)[C@@H](c2ccccc2)O1

nearest known ligand 0.42

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 1/20 0.42
HCRTR2 O43614 7/20 0.39
HCRTR1 O43613 5/20 0.39
ALDH1A1 P00352 1/20 0.37
TBXA2R P21731 1/20 0.36
SLC5A2 P31639 3/20 0.36
CYP2C19 P33261 1/20 0.35
CYP2D6 P10635 1/20 0.35
PTGS2 P35354 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14626066 1.00 CYP3A4 (0.42) CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1
SCHEMBL16808485 1.00 CYP3A4 (0.42) CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1
SCHEMBL18801954 1.00 CYP3A4 (0.42) CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1
SCHEMBL17093240 0.86 CYP3A4 (0.40) CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1
SCHEMBL17093290 0.86 CYP3A4 (0.40) CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1
SCHEMBL16808524 0.86 CYP3A4 (0.40) CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1
SCHEMBL18802267 0.86 CYP3A4 (0.40) CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1
SCHEMBL18176800 0.83 CYP3A4 (0.39) CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1
SCHEMBL18176799 0.83 CYP3A4 (0.39) CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1
SCHEMBL17827377 0.83 CYP3A4 (0.39) CYP3A4MAPK1HCRTR2HCRTR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007005935-A2 NOREPINEPHRINE TRANSPORTER RADIOTRACERS AND METHODS OF SYNTHESES THEREOF MOLECULAR NEUROIMAGING, LLC (US) 2007-01-11 WO disclosed
WO-2007005935-A2 NOREPINEPHRINE TRANSPORTER RADIOTRACERS AND METHODS OF SYNTHESES THEREOF MOLECULAR NEUROIMAGING, LLC (US) 2007-01-11 WO disclosed