Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.90 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.90 |
| ▸ | POLB | P06746 | 4/20 | 0.90 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | ILK | Q13418 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GPR55 | Q9Y2T6 | 3/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30203865 | 1.00 | MAPT (0.90) | MAPTKDM4EPOLBRAB9ANPSR1 | |
| SCHEMBL14396306 | 0.82 | MAPT (0.70) | MAPTKDM4EPOLBRAB9ANPSR1 | |
| SCHEMBL14396300 | 0.81 | MAPT (0.63) | MAPTKDM4EPOLBRAB9ANPSR1 | |
| SCHEMBL12768521 | 0.78 | MAPT (0.75) | MAPTKDM4EPOLBRAB9ANPSR1 | |
| SCHEMBL29693710 | 0.78 | KDM4E (1.00) | MAPTKDM4EPOLBRAB9ANPSR1 | |
| SCHEMBL7192101 | 0.78 | KDM4E (1.00) | MAPTKDM4EPOLBRAB9ANPSR1 | |
| SCHEMBL687435 | 0.77 | KDM4E (0.71) | MAPTKDM4EPOLBRAB9ANPSR1 | |
| SCHEMBL30204288 | 0.76 | MAPT (0.75) | MAPTKDM4EPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL5269762 | 0.76 | MAPT (0.75) | MAPTKDM4EPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL18292277 | 0.75 | MEN1 (0.61) | MAPTKDM4EPOLBNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |
| US-20070203224-A1 | SMALL-MOLECULES FOR TREATING CANCER AND ABNORMAL CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2007-08-30 | — | — | US | disclosed |
| US-20070203224-A1 | SMALL-MOLECULES FOR TREATING CANCER AND ABNORMAL CELL PROLIFERATION DISORDERS | UNIVERSITY OF SOUTHERN CALIFORNIA | 2007-08-30 | — | — | US | disclosed |