Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 4/20 | 0.47 |
| ▸ | KDR | P35968 | 9/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.38 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.38 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14530632 | 0.92 | KDR (0.46) | LCKKDREGFRCHEK1SIK2 | |
| SCHEMBL5313703 | 0.92 | LCK (0.39) | LCKKDR | |
| SCHEMBL5314665 | 0.89 | LCK (0.40) | LCKKDR | |
| SCHEMBL14531020 | 0.88 | LCK (0.49) | LCKKDREGFRCHEK1SIK2 | |
| SCHEMBL14530838 | 0.85 | KDR (0.48) | LCKKDRCHEK1SIK2SIK3 | |
| SCHEMBL14531379 | 0.84 | KDR (0.39) | LCKKDR | |
| SCHEMBL5315530 | 0.81 | KDR (0.39) | LCKKDR | |
| SCHEMBL5335400 | 0.81 | KDR (0.53) | LCKKDR | |
| SCHEMBL5339002 | 0.78 | KDR (0.43) | KDR | |
| SCHEMBL5379687 | 0.77 | LCK (0.43) | LCKKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |