Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAK1 | Q13153 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | ROS1 | P08922 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332513 | 1.00 | PAK1 (0.38) | PAK1SYKLRRK2FFAR4FFAR1 | |
| SCHEMBL5333336 | 0.93 | SYK (0.33) | PAK1SYKLRRK2FFAR4FFAR1 | |
| SCHEMBL5333342 | 0.93 | SYK (0.33) | PAK1SYKLRRK2FFAR4FFAR1 | |
| SCHEMBL5332464 | 0.86 | FFAR1 (0.35) | PAK1SYKLRRK2FFAR4FFAR1 | |
| SCHEMBL5332468 | 0.86 | FFAR1 (0.35) | PAK1SYKLRRK2FFAR4FFAR1 | |
| SCHEMBL5331688 | 0.85 | LRRK2 (0.34) | PAK1SYKLRRK2FFAR4FFAR1 | |
| SCHEMBL5331684 | 0.85 | LRRK2 (0.34) | PAK1SYKLRRK2FFAR4FFAR1 | |
| SCHEMBL5332660 | 0.76 | FFAR1 (0.35) | PAK1FFAR4FFAR1PDK2LMNA | |
| SCHEMBL5324551 | 0.76 | PAK1 (0.33) | PAK1FFAR4FFAR1LMNA | |
| SCHEMBL5329170 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147829-A1 | AZOLOPYRIMIDINE COMPOUNDS AND THEIR USE FOR CONTROLLING HARMFUL FUNGI | BASF SE (DE) | 2007-12-27 | — | — | WO | disclosed |
| EP-1740553-A1 | ARYL GLYCINAMIDE DERIVATIVES AND THEIR USE AS NK1 ANTAGONISTS AND SEROTONIN REUPTAKE INHIBITHORS | AstraZeneca AB (SE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005100325-A1 | ARYL GLYCINAMIDE DERIVATIVES AND THEIR USE AS NK1 ANTAGONISTS AND SEROTONIN REUPTAKE INHIBITHORS | ASTRAZENECA AB (SE) | 2005-10-27 | — | — | WO | disclosed |