Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GPER1 | Q99527 | 3/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL916447 | 0.81 | MAPT (0.43) | MCL1MEN1KMT2APOLBAR | |
| SCHEMBL916069 | 0.79 | AR (0.38) | MEN1KMT2APOLBARMAPT | |
| SCHEMBL916392 | 0.77 | MAPT (0.54) | MCL1MEN1KMT2APOLBAR | |
| SCHEMBL916776 | 0.76 | MAPT (0.44) | MEN1KMT2APOLBARMAPT | |
| SCHEMBL917264 | 0.74 | ESR1 (0.37) | MCL1MEN1KMT2APOLBAR | |
| SCHEMBL916037 | 0.69 | ESR1 (0.37) | MCL1MEN1KMT2APOLBAR | |
| SCHEMBL916165 | 0.69 | KMT2A (0.55) | MCL1MEN1KMT2APOLBAR | |
| SCHEMBL915341 | 0.67 | KMT2A (0.52) | MCL1MEN1KMT2APOLBAR | |
| SCHEMBL915287 | 0.65 | KMT2A (0.52) | MCL1MEN1KMT2APOLBAR | |
| SCHEMBL21105585 | 0.64 | GPER1 (0.71) | MCL1MEN1KMT2APOLBAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007019180-A2 | COMPOUNDS FOR BINDING TO ERALPHA/BETA AND GPR30, METHODS OF TREATING DISEASE STATES AND CONDITIONS MEDIATED THROUGH THESE RECEPTORS AND IDENTIFICATION THEREOF | SCIENCE & TECHNOLOGY CORPORATION @ UNM (US) | 2007-02-15 | — | — | WO | disclosed |