Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | BIRC5 | O15392 | 2/20 | 0.37 |
| ▸ | IL2 | P60568 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.34 |
| ▸ | AGPAT2 | O15120 | 2/20 | 0.34 |
| ▸ | EIF4E | P06730 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000098 | 0.83 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6001574 | 0.76 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6000158 | 0.76 | MAPT (0.54) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6001366 | 0.72 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL19785385 | 0.70 | PDE2A (0.47) | MEN1KMT2AALDH1A1BIRC5IL2 | |
| SCHEMBL6002064 | 0.70 | MAPT (0.73) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL31196638 | 0.67 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL5307613 | 0.67 | MAPT (0.68) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL6000106 | 0.67 | MAPT (0.77) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL15503719 | 0.67 | MAPT (1.00) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070148185-A1 | Novel therapeutic target for protozoal diseases | VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY | 2007-06-28 | — | — | US | claimed |
| WO-2007047579-A2 | A NOVEL THERAPEUTIC TARGET FOR PROTOZOAL DISEASES | VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) | 2007-04-26 | — | — | WO | claimed |