Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.64 |
| ▸ | CNR1 | P21554 | 3/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | SCN4A | P35499 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14051349 | 0.77 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL14566339 | 0.77 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL14051262 | 0.76 | CNR2 (1.00) | CNR2CNR1IDO1 | |
| SCHEMBL14566340 | 0.76 | CNR2 (0.54) | CNR2CNR1IDO1NUDT1 | |
| SCHEMBL5084514 | 0.75 | CNR2 (0.57) | CNR2CNR1IDO1NOTUMCYP2D6 | |
| SCHEMBL14051223 | 0.75 | CNR2 (1.00) | CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL5088053 | 0.74 | CNR2 (0.97) | CNR2CNR1 | |
| SCHEMBL14051353 | 0.73 | CNR2 (0.52) | CNR2CNR1IDO1NOTUMNUDT1 | |
| SCHEMBL14051263 | 0.73 | CNR2 (1.00) | CNR2CNR1MAPK1 | |
| SCHEMBL5085295 | 0.73 | CNR2 (0.54) | CNR2CNR1IDO1NOTUMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008116816-A1 | COMBINATION OF CB2 LIGAND AND PARACETAMOL | GLAXO GROUP LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |
| WO-2007022937-A1 | PYRIDAZINE DERIVATIVES WITH ANTIINFLAMMATORY ACTIVITY | GLAXO GROUP LIMITED (GB) | 2007-03-01 | — | — | WO | disclosed |
| WO-2007022937-A1 | PYRIDAZINE DERIVATIVES WITH ANTIINFLAMMATORY ACTIVITY | GLAXO GROUP LIMITED (GB) | 2007-03-01 | — | — | WO | disclosed |