Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5312270 | 1.00 | HMGCR (0.65) | HMGCR | |
| SCHEMBL5313531 | 1.00 | HMGCR (0.65) | HMGCR | |
| SCHEMBL5478560 | 0.90 | HMGCR (0.54) | HMGCR | |
| SCHEMBL5992264 | 0.88 | HMGCR (0.83) | HMGCR | |
| SCHEMBL5993062 | 0.88 | HMGCR (0.83) | HMGCR | |
| SCHEMBL5223655 | 0.85 | HMGCR (0.78) | HMGCR | |
| SCHEMBL6409537 | 0.85 | HMGCR (0.75) | HMGCR | |
| SCHEMBL5220259 | 0.85 | HMGCR (0.75) | HMGCR | |
| SCHEMBL5223826 | 0.84 | HMGCR (0.64) | HMGCR | |
| SCHEMBL5493958 | 0.82 | HMGCR (0.68) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007042910-A1 | IMIDAZOLES AND THEIR USE AS HMG-COA REDUCTASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 2007-04-19 | — | — | WO | disclosed |