SCHEMBL5332264

SCHEMBL5332264

O=C(NC1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(O)cc2)c1S(=O)(=O)CO

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 9/20 0.65
CNR1 P21554 8/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4911421 0.86 CNR1 (0.85) CNR2CNR1
SCHEMBL4250869 0.84 CNR1 (0.91) CNR2CNR1
SCHEMBL4912659 0.82 CNR1 (0.70) CNR2CNR1
SCHEMBL4633760 0.81 CNR1 (0.90) CNR2CNR1
SCHEMBL4110658 0.81 CNR1 (0.54) CNR2CNR1
SCHEMBL276799 0.79 CNR1 (1.00) CNR2CNR1
SCHEMBL12053836 0.78 CNR1 (1.00) CNR2CNR1
SCHEMBL12053987 0.77 CNR1 (0.72) CNR2CNR1
SCHEMBL12053983 0.77 CNR1 (0.74) CNR2CNR1
SCHEMBL12053833 0.77 CNR1 (0.87) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1831177-A1 THERAPEUTIC AGENTS AstraZeneca AB (SE) 2007-09-12 EP disclosed
WO-2006067443-A1 THERAPEUTIC AGENTS ASTRAZENECA AB (SE) 2006-06-29 WO disclosed