Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 7/20 | 0.69 |
| ▸ | CNR2 | P34972 | 3/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3999243 | 0.90 | CNR1 (0.70) | CNR1CNR2KCNH2 | |
| SCHEMBL13191019 | 0.90 | CNR2 (0.57) | CNR1CNR2KCNH2 | |
| SCHEMBL2873286 | 0.90 | CNR1 (0.70) | CNR1CNR2KCNH2 | |
| SCHEMBL4464625 | 0.90 | CNR1 (0.75) | CNR1CNR2KCNH2 | |
| Hydrochloric Acid SCHEMBL6543063 | 0.89 | CNR1 (0.69) | CNR1CNR2KCNH2 | |
| SCHEMBL2874753 | 0.87 | CNR1 (0.66) | CNR1CNR2KCNH2 | |
| SCHEMBL4466452 | 0.85 | CNR2 (0.71) | CNR1CNR2KCNH2 | |
| SCHEMBL4462642 | 0.85 | CNR1 (0.71) | CNR1CNR2KCNH2 | |
| SCHEMBL12053976 | 0.84 | CNR1 (0.76) | CNR1CNR2KCNH2 | |
| SCHEMBL4892080 | 0.83 | CNR1 (0.69) | CNR1CNR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1855675-A1 | USE OF A PYRAZOLE DERIVATIVE FOR PREPARING MEDICINES USEFUL FOR PREVENTING OR TREATING RENAL DISEASES | Sanofi-Aventis (FR) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006090047-A1 | USE OF A PYRAZOLE DERIVATIVE FOR PREPARING MEDICINES USEFUL FOR PREVENTING OR TREATING RENAL DISEASES | SANOFI-AVENTIS (FR) | 2006-08-31 | — | — | WO | disclosed |
| EP-1583758-A1 | DERIVATIVE OF 5-(4-BROMOPHENYL)-1-(2,4-DICHLOROPHENLY)-4-ETHYL-N-(PIPERIDINE-1-YL)-1H-PYRAZOL-3-CARBOXAMIDE, THE PREPARATION AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004058744-A1 | DERIVATIVE OF 5-(4-BROMOPHENYL)-1-(2,4-DICHLOROPHENLY)-4-ETHYL-N-(PIPERIDINE-1-YL)-1H-PYRAZOL-3-CARBOXAMIDE, THE PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2004-07-15 | — | — | WO | disclosed |