Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | PRKAG1 | P54619 | 9/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 9/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 9/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 8/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 7/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 7/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 7/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533376 | 0.94 | KCNH2 (0.43) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL25239780 | 0.89 | TSHR (0.37) | KCNH2HRH3TSHR | |
| SCHEMBL19662088 | 0.86 | KCNH2 (0.50) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| Water SCHEMBL7156214 | 0.83 | TSHR (0.54) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL17414393 | 0.80 | TSHR (0.56) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL28414 | 0.80 | TSHR (0.56) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL28318493 | 0.78 | TSHR (0.54) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL972955 | 0.77 | KCNH2 (0.34) | KCNH2HRH3NPC1POLBMAPT | |
| SCHEMBL9772734 | 0.77 | KCNH2 (0.44) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL9772749 | 0.77 | SLC6A2 (0.44) | KCNH2HRH3PRKAG1PRKAA1PRKAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415763-B1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | UBE INDUSTRIES (JP) | 2016-01-27 | — | — | EP | disclosed |
| CN-103965099-A | Pyridylaminoacetic Acid Compound | UBE INDUSTRIES | 2014-08-06 | — | — | CN | disclosed |
| CN-101970410-B | Pyridylaminoacetic acid compounds | UBE INDUSTRIES | 2014-06-25 | — | — | CN | disclosed |
| US-20140113907-A1 | PYRIDYLAMINOACETIC ACID COMPOUND | UBE INDUSTRIES, LTD. (JP) | 2014-04-24 | — | — | US | disclosed |
| US-8648097-B2 | Pyridylaminoacetic acid compound | UBE INDUSTRIES, LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| US-20120190852-A1 | MEDICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF GLAUCOMA | UBE INDUSTRIES, LTD. (JP) | 2012-07-26 | — | — | US | disclosed |
| EP-2415763-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | Ube Industries, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-20110054172-A1 | PYRIDYLAMINOACETIC ACID COMPOUND | UBE CORPORATION (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2264009-A1 | PYRIDYLAMINOACETIC ACID COMPOUND | Ube Industries, Ltd. (JP) | 2010-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140113907-A1 | PYRIDYLAMINOACETIC ACID COMPOUND | PTGER2, PTGER1, PTGDR2 | KCNH2 1300/4885HRH3 100/4885PRKAG1 755/4885 |
| US-20110054172-A1 | PYRIDYLAMINOACETIC ACID COMPOUND | PTGER2, PTGER1, PTGDR2 | KCNH2 1354/4885HRH3 107/4885PRKAG1 647/4885 |
| US-20120190852-A1 | MEDICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF GLAUCOMA | F12, C1S, AKR1C3 | KCNH2 211/4885HRH3 579/4885PRKAG1 3699/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.