Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5311745 | 0.84 | MAPT (0.70) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5463629 | 0.83 | MEN1 (0.72) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5314760 | 0.81 | MEN1 (0.57) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5369271 | 0.81 | MEN1 (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5315121 | 0.77 | GAA (0.48) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5371558 | 0.73 | CLK1 (0.47) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL5466877 | 0.72 | MEN1 (0.84) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL5369266 | 0.72 | MEN1 (0.82) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5334395 | 0.71 | EGFR (0.51) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5467182 | 0.71 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | claimed |
| WO-2007056215-A9 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA INC (US) | 2007-09-13 | — | — | WO | disclosed |
| WO-2007056215-A2 | N-ARYL-THIENOPYRIMIDIN-4-AMINES AND THE USE THEREOF | CYTOVIA, INC. (US) | 2007-05-18 | — | — | WO | disclosed |