Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.61 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.55 |
| ▸ | ASPH | Q12797 | 1/20 | 0.55 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5308937 | 0.83 | HTT (0.64) | EGLN1BBOX1ASPHKDM8KDM4E | |
| SCHEMBL2399702 | 0.82 | MEN1 (0.77) | EGLN1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL5333747 | 0.81 | EGLN1 (0.68) | EGLN1BBOX1ASPHKDM8KDM4E | |
| SCHEMBL8248486 | 0.81 | EGLN1 (0.71) | EGLN1KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL2382364 | 0.81 | EGLN1 (0.78) | EGLN1KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL15846316 | 0.81 | EGLN1 (0.66) | EGLN1BBOX1ASPHKDM8KDM4E | |
| SCHEMBL15846934 | 0.80 | EGLN1 (0.70) | EGLN1BBOX1ASPHKDM8KDM4E | |
| SCHEMBL8244097 | 0.80 | EGLN1 (0.69) | EGLN1KDM4EHTTALDH1A1MEN1 | |
| SCHEMBL8248121 | 0.79 | EGLN1 (0.68) | EGLN1BBOX1ASPHKDM8KDM4E | |
| SCHEMBL17181725 | 0.79 | EGLN1 (0.69) | EGLN1BBOX1ASPHKDM8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | claimed |
| WO-2007038571-A2 | PROLYL HYDROXYLASE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-04-05 | — | — | WO | disclosed |