Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.55 |
| ▸ | TBK1 | Q9UHD2 | 8/20 | 0.44 |
| ▸ | LCK | P06239 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | WNK1 | Q9H4A3 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5336891 | 0.92 | KDR (0.55) | KDRTBK1LCKACHE | |
| SCHEMBL5311424 | 0.92 | KDR (0.53) | KDRTBK1LCKACHEWNK1 | |
| SCHEMBL5334772 | 0.86 | KDR (0.55) | KDRTBK1LCKWNK1 | |
| SCHEMBL5335398 | 0.85 | KDR (0.52) | KDRTBK1LCK | |
| SCHEMBL5310881 | 0.84 | KDR (0.53) | KDRTBK1LCKACHEBACE1 | |
| SCHEMBL5313051 | 0.83 | KDR (0.46) | KDRTBK1LCKACHE | |
| SCHEMBL5313599 | 0.83 | KDR (0.52) | KDRTBK1LCKACHE | |
| SCHEMBL5314663 | 0.82 | KDR (0.49) | KDRTBK1LCK | |
| SCHEMBL5311426 | 0.80 | KDR (0.52) | KDRTBK1LCKWNK1 | |
| SCHEMBL5339092 | 0.80 | KDR (0.56) | KDRTBK1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058482-A1 | NOVEL INHIBITORS OF PROTEIN KINASE | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |