SCHEMBL5335030

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5334868	0.94	DRD3 (0.60)	DRD3DRD2DRD4HRH3DRD1
	SCHEMBL5332526	0.93	DRD3 (0.56)	DRD3DRD2DRD4HRH3DRD1
	SCHEMBL5334375	0.93	DRD3 (0.55)	DRD3DRD2DRD4HRH3DRD1
	SCHEMBL5337878	0.88	DRD3 (0.61)	DRD3DRD2DRD4HRH3DRD1
	SCHEMBL5340409	0.88	DRD3 (0.57)	DRD3DRD2DRD4DRD1NPC1
	SCHEMBL5332289	0.87	DRD3 (0.57)	DRD3DRD2DRD4HRH3DRD1
	SCHEMBL5343031	0.83	DRD3 (0.63)	DRD3DRD2DRD4DRD1NPC1
	SCHEMBL5334548	0.83	DRD3 (0.59)	DRD3DRD2DRD4HRH3DRD1
	SCHEMBL5336968	0.82	DRD3 (0.59)	DRD3DRD2DRD4DRD1NPC1
	SCHEMBL3034408	0.81	SOAT1 (0.48)	DRD2HTR1AHTR2AHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.