⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4806763 | 0.65 | — | — | |
| SCHEMBL534389 | 0.61 | — | — | |
| SCHEMBL534359 | 0.61 | — | — | |
| SCHEMBL549035 | 0.60 | — | — | |
| Fluoride SCHEMBL2590705 | 0.40 | — | — | |
| SCHEMBL415721 | 0.34 | — | — | |
| SCHEMBL4311227 | 0.34 | MEN1 (0.33) | — | |
| Benzene SCHEMBL1951518 | 0.34 | TP53 (0.38) | — | |
| SCHEMBL42968 | 0.33 | GRIN2D (0.33) | — | |
| SCHEMBL22689491 | 0.33 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195304-A2 | ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS | Advinus Therapeutics Private Limited (IN) | 2010-06-16 | — | — | EP | claimed |
| WO-2009047798-A2 | ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND MEDICINAL APPLICATIONS | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2009-04-16 | — | — | WO | claimed |
| US-9957248-B2 | Substituted 5-hydroxy-2-heteroaryl-3-phenylpentanonitrile derivatives, processes for their preparation and their use as herbicides and/or plant growth regulators | BAYER CROPSCIENCE AKTIENGESELLSHAFT (DE) | 2018-05-01 | — | — | US | disclosed |
| EP-2462124-B9 | MESOIONIC PESTICIDES | DU PONT (US) | 2017-08-23 | — | — | EP | disclosed |
| US-9730448-B2 | Tetrazolinone compound and use of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-08-15 | — | — | US | disclosed |
| US-20170166549-A1 | Substituted 5-hydroxy-2-heteroaryl-3-phenylpentanonitrile derivatives, processes for their preparation and their use as herbicides and/or plant growth regulators | BAYER CROPSCIENCE AKTIENGESELLSHAFT (DE) | 2017-06-15 | — | — | US | disclosed |
| US-20160205935-A1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-07-21 | — | — | US | disclosed |
| EP-3040332-A1 | TETRAZOLINONE COMPOUND AND USE OF SAME | Sumitomo Chemical Company, Limited (JP) | 2016-07-06 | — | — | EP | disclosed |
| CN-105315319-A | Hepatitis C virus inhibitor and application thereof | NANJING SANHOME PHARMACEUTICAL CO LTD | 2016-02-10 | — | — | CN | disclosed |
| EP-2415763-B1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | UBE INDUSTRIES (JP) | 2016-01-27 | — | — | EP | disclosed |
| WO-2015197187-A1 | PYRAZOLYL-BASED CARBOXAMIDES V | Grünenthal GmbH (DE) | 2015-12-30 | — | — | WO | disclosed |
| EP-2264009-A1 | PYRIDYLAMINOACETIC ACID COMPOUND | Ube Industries, Ltd. (JP) | 2010-12-22 | — | — | EP | disclosed |
| CN-101842358-A | Fluorine-containing organosulfur compound and pesticidal composition comprising the same | SUMITOMO CHEMICAL CO | 2010-09-22 | — | — | CN | disclosed |
| US-20100048532-A1 | Benzimidazole Derivatives as Selective Acid Pump Inhibitors | RAQUALIA PHARMA INC. (JP) | 2010-02-25 | — | — | US | disclosed |
| CN-101528750-A | Benzimidazole derivatives as selective acid pump inhibitors | PFIZER JAPAN INC (JP) | 2009-09-09 | — | — | CN | disclosed |
| EP-2081939-A1 | BENZIMIDAZOLE DERIVATIVES AS SELECTIVE ACID PUMP INHIBITORS | RaQualia Pharma Inc (JP) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008114123-A1 | SPIRO BENZIMIDAZOLE DERIVATIVES AS ACID PUMP INHIBITORS | RAQUALIA PHARMA INC. (JP) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008035195-A1 | BENZIMIDAZOLE DERIVATIVES AS SELECTIVE ACID PUMP INHIBITORS | RAQUALIA PHARMA INC. (JP) | 2008-03-27 | — | — | WO | disclosed |
| WO-2007072142-A2 | BENZIMIDAZOLE-5-CARBOXAMIDE DERIVATIVES | PFIZER JAPAN INC. (JP) | 2007-06-28 | — | — | WO | disclosed |
| EP-0556123-A1 | Pyrethrinoid esters of thiazolylalcohols, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-08-18 | — | — | EP | disclosed |