Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 1.00 |
| ▸ | NR1H2 | P55055 | 8/20 | 1.00 |
| ▸ | NR1H3 | Q13133 | 8/20 | 1.00 |
| ▸ | PPARG | P37231 | 14/20 | 0.80 |
| ▸ | PPARD | Q03181 | 10/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4234370 | 0.94 | PPARA (0.88) | PPARANR1H2NR1H3PPARGPPARD | |
| SCHEMBL5008698 | 0.89 | PPARA (1.00) | PPARANR1H2NR1H3PPARGPPARD | |
| SCHEMBL5335773 | 0.88 | PPARA (0.79) | PPARANR1H2NR1H3PPARGPPARD | |
| SCHEMBL5943621 | 0.88 | PPARG (1.00) | PPARANR1H2NR1H3PPARGPPARD | |
| SCHEMBL5012506 | 0.88 | PPARG (0.83) | PPARANR1H2NR1H3PPARGPPARD | |
| SCHEMBL5338721 | 0.88 | PPARA (0.79) | PPARANR1H2NR1H3PPARGPPARD | |
| SCHEMBL4229985 | 0.88 | PPARG (0.90) | PPARANR1H2NR1H3PPARGPPARD | |
| SCHEMBL4233554 | 0.88 | PPARG (0.90) | PPARANR1H2NR1H3PPARGPPARD | |
| SCHEMBL14465320 | 0.87 | PPARG (0.83) | PPARANR1H2NR1H3PPARGPPARD | |
| SCHEMBL14010328 | 0.87 | PPARA (0.77) | PPARANR1H2NR1H3PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060178398-A1 | Therapeutic compounds for treating dyslipidemic conditions | ADAMS ALAN D | 2006-08-10 | — | — | US | claimed |
| WO-2007081335-A1 | THERAPEUTIC COMPOUNDS FOR TREATING DYSLIPIDEMIC CONDITIONS | MERCK & CO., INC. (US) | 2007-07-19 | — | — | WO | disclosed |
| US-20060178398-A1 | Therapeutic compounds for treating dyslipidemic conditions | ADAMS ALAN D | 2006-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178398-A1 | Therapeutic compounds for treating dyslipidemic conditions | NR1H2, NR1H3, LDLR | PPARA 118/4885NR1H2 1/4885NR1H3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.