Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.61 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003334 | 1.00 | HRH3 (0.61) | HRH3KCNH2ADRA1AHRH2HRH1 | |
| SCHEMBL2004698 | 0.89 | HRH3 (0.76) | HRH3KCNH2ADRA1A | |
| SCHEMBL502676 | 0.85 | HRH3 (0.80) | HRH3KCNH2ADRA1A | |
| SCHEMBL2005250 | 0.83 | HRH3 (0.53) | HRH3KCNH2ADRA1AHRH2HRH1 | |
| SCHEMBL5336265 | 0.83 | HRH3 (0.53) | HRH3KCNH2ADRA1AHRH2HRH1 | |
| SCHEMBL2008001 | 0.81 | HRH3 (0.59) | HRH3KCNH2ADRA1AHRH2HRH1 | |
| SCHEMBL2008462 | 0.81 | HRH3 (0.55) | HRH3KCNH2ADRA1AHRH2HRH1 | |
| SCHEMBL5333167 | 0.80 | HRH3 (0.63) | HRH3KCNH2ADRA1A | |
| SCHEMBL2004044 | 0.80 | HRH3 (0.63) | HRH3KCNH2ADRA1A | |
| SCHEMBL2005484 | 0.80 | HRH3 (0.78) | HRH3KCNH2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757594-A1 | QUINAZOLINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |