Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 14/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337425 | 1.00 | P2RY12 (0.46) | P2RY12MEN1HSD17B10KMT2AIDH1 | |
| SCHEMBL5264838 | 0.85 | P2RY12 (0.58) | P2RY12MEN1 | |
| SCHEMBL5265404 | 0.84 | P2RY12 (0.49) | P2RY12MEN1HSD17B10KMT2AALDH1A1 | |
| SCHEMBL5264901 | 0.83 | P2RY12 (0.42) | P2RY12MEN1KMT2AALDH1A1 | |
| SCHEMBL5270002 | 0.83 | P2RY12 (0.44) | P2RY12MEN1 | |
| SCHEMBL5375467 | 0.83 | P2RY12 (0.44) | P2RY12MEN1 | |
| SCHEMBL5340280 | 0.82 | P2RY12 (0.51) | P2RY12MEN1KMT2AALDH1A1 | |
| SCHEMBL5266625 | 0.82 | P2RY12 (0.51) | P2RY12MEN1KMT2AALDH1A1 | |
| SCHEMBL5265481 | 0.81 | P2RY12 (0.43) | P2RY12MEN1 | |
| SCHEMBL5265488 | 0.81 | P2RY12 (0.43) | P2RY12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |