⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL533426 | 0.90 | PTGER2 (0.32) | — | |
| SCHEMBL533751 | 0.88 | — | — | |
| SCHEMBL3458643 | 0.87 | PTGER2 (0.32) | — | |
| SCHEMBL3458639 | 0.82 | — | — | |
| SCHEMBL533749 | 0.82 | PTGER2 (0.39) | — | |
| SCHEMBL533748 | 0.81 | SLC1A3 (0.32) | — | |
| SCHEMBL533750 | 0.79 | USP2 (0.31) | — | |
| SCHEMBL533427 | 0.78 | PTGER2 (0.47) | — | |
| SCHEMBL534324 | 0.77 | PTGER2 (0.38) | — | |
| SCHEMBL3458635 | 0.77 | PTGER2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8648097-B2 | Pyridylaminoacetic acid compound | UBE INDUSTRIES, LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| EP-2415763-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | Ube Industries, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |