Known targets — ChEMBL curated mechanism
SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9A
The experimentally established mechanism targets of Gluconic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Gluconic Acid SCHEMBL27700133 | 1.00 | PDE4A (0.70) | PDE4ALMNAUSP2SLCO1B1ALDH1A1 | |
| Gluconic Acid SCHEMBL29564356 | 0.92 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Gluconic Acid SCHEMBL28152796 | 0.92 | PDE4A (0.76) | PDE4ALMNAUSP2SLCO1B1L3MBTL1 | |
| Octadecylamine SCHEMBL28377198 | 0.86 | PDE4A (0.61) | PDE4ALMNAUSP2SLCO1B1ALDH1A1 | |
| Hexadecylamine SCHEMBL28383523 | 0.86 | PDE4A (0.61) | PDE4ALMNAUSP2SLCO1B1ALDH1A1 | |
| Dodecylamine SCHEMBL6348883 | 0.86 | PDE4A (0.61) | PDE4ALMNAUSP2SLCO1B1ALDH1A1 | |
| Gluconic Acid SCHEMBL29034483 | 0.86 | PDE4A (0.86) | PDE4ALMNAUSP2SLCO1B1ALDH1A1 | |
| Gluconic Acid SCHEMBL30529944 | 0.86 | PDE4A (0.86) | PDE4ALMNAUSP2SLCO1B1ALDH1A1 | |
| Gluconic Acid SCHEMBL31354688 | 0.86 | PDE4A (0.86) | PDE4ALMNAUSP2SLCO1B1ALDH1A1 | |
| Gluconic Acid SCHEMBL28168949 | 0.86 | PDE4A (0.86) | PDE4ALMNAUSP2SLCO1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1797926-A1 | SURFACTANT COMPOSITION | Furukawa Techno Material Co., Ltd (JP) | 2007-06-20 | — | — | EP | disclosed |