Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5334891 | 0.81 | ESR2 (0.37) | ESR2ESR1 | |
| SCHEMBL5338955 | 0.76 | ESR1 (0.32) | ESR2ESR1 | |
| SCHEMBL5726973 | 0.74 | ESR2 (0.53) | ESR2ESR1 | |
| SCHEMBL14590333 | 0.71 | ESR2 (0.54) | ESR2ESR1 | |
| SCHEMBL5342870 | 0.71 | ESR2 (0.53) | ESR2ESR1 | |
| SCHEMBL5341176 | 0.69 | ESR2 (0.62) | ESR2ESR1 | |
| SCHEMBL5334894 | 0.67 | ESR1 (0.31) | ESR2ESR1 | |
| SCHEMBL5904403 | 0.62 | ESR2 (0.59) | ESR2ESR1 | |
| SCHEMBL5904399 | 0.62 | ESR2 (0.59) | ESR2ESR1 | |
| SCHEMBL5335858 | 0.62 | ESR2 (0.55) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7157604-B2 | Selective estrogen receptor modulators | MERCK & CO., INC. (US) | 2007-01-02 | — | — | US | disclosed |
| US-20040210080-A1 | Selective estrogen receptor modulators | MERCK & CO., INC. | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040210080-A1 | Selective estrogen receptor modulators | GPER1, ESR2, ESR1 | ESR2 2/4885ESR1 3/4885CYP19A1 30/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.