Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4173662 | 1.00 | ERBB2 (0.64) | ERBB2EGFR | |
| SCHEMBL4180711 | 0.89 | ERBB2 (0.71) | ERBB2EGFR | |
| SCHEMBL4171631 | 0.88 | ERBB2 (0.65) | ERBB2EGFR | |
| SCHEMBL4176232 | 0.87 | ERBB2 (0.68) | ERBB2EGFR | |
| SCHEMBL4177522 | 0.86 | ERBB2 (0.64) | ERBB2EGFR | |
| SCHEMBL4387806 | 0.83 | ERBB2 (0.76) | ERBB2EGFR | |
| SCHEMBL4180207 | 0.82 | ERBB2 (0.63) | ERBB2EGFR | |
| SCHEMBL4382756 | 0.81 | EGFR (0.73) | ERBB2EGFR | |
| SCHEMBL4030835 | 0.81 | ERBB2 (0.68) | ERBB2EGFR | |
| SCHEMBL3378119 | 0.81 | ERBB2 (0.77) | ERBB2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858884-A1 | INDAZOLYLAMINO QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | AstraZeneca AB (SE) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006092573-A1 | INDAZOLYLAMINO QIONAZOLINE DERIVATIVES AS ANTITUMOR AGENTS | ASTRAZENECA AB (SE) | 2006-09-08 | — | — | WO | disclosed |