SCHEMBL534067

SCHEMBL534067

C=CC(=O)OCCC[Si](CC)(OC)OC

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.58
HPGD P15428 1/20 0.58
ALDH1A1 P00352 4/20 0.53
CYP3A4 P08684 2/20 0.53
TP53 P04637 3/20 0.44
HIF1A Q16665 3/20 0.44
HSD17B10 Q99714 1/20 0.44
THRB P10828 2/20 0.41
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 4/20 0.35
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28183076 0.98 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16536722 0.95 TSHR (0.56) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL30771880 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL30771903 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL30771904 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL30771882 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16286809 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL30771901 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL16537901 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53
SCHEMBL31421922 0.94 TSHR (0.59) TSHRHPGDALDH1A1CYP3A4TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106867033-B A kind of inorganic matter cladding organic silicon fibre retardant of alternative antimony oxide and the preparation method and application thereof 广东优科艾迪高分子材料有限公司 2019-01-25 CN claimed
EP-3268411-A1 A POLYORGANOSILOXANE AND A MOISTURE AND RADIATION CURABLE ADHESIVE COMPOSITION COMPRISING THE SAME Henkel IP & Holding GmbH (DE) 2018-01-17 EP claimed
CN-106957396-A A kind of automatically cleaning wear-resisting type organosilicon toughener and preparation method and application 广东优科艾迪高分子材料有限公司 2017-07-18 CN claimed
CN-106947035-A A kind of anti-dripping melt type organic sesqui siloxane fire retardant and preparation method and application 广东优科艾迪高分子材料有限公司 2017-07-14 CN claimed
CN-106947031-A A kind of novel fluorine siloxane flame retardant and preparation method and application 广东优科艾迪高分子材料有限公司 2017-07-14 CN claimed
CN-106867033-A A kind of inorganic matter cladding organic silicon fibre retardant of alternative antimony oxide and preparation method and application 广东优科艾迪高分子材料有限公司 2017-06-20 CN claimed
CN-106866971-A A kind of weather-proof low-temperature type organosilicon impact modifier and preparation method and application 广东优科艾迪高分子材料有限公司 2017-06-20 CN claimed
WO-2016141547-A1 A POLYORGANOSILOXANE AND A MOISTURE AND RADIATION CURABLE ADHESIVE COMPOSITION COMPRISING THE SAME Henkel IP Holding GmbH (DE) 2016-09-15 WO claimed
EP-3819291-B1 OXIME ESTER COMPOUND AND PHOTOPOLYMERIZATION INITIATOR CONTAINING SAME ADEKA CORP (JP) 2026-04-15 EP disclosed
EP-4563609-A1 PHOTOCURABLE COMPOSITION, CURED PRODUCT OF SAME, AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-04 EP disclosed
CN-119585328-A Photocurable composition, cured product thereof, and coated article 信越化学工业株式会社 2025-03-07 CN disclosed
CN-110546134-B Oxime ester compound and photopolymerization initiator containing the same 株式会社艾迪科 2024-12-20 CN disclosed
CN-112004800-B Oxime ester compound and photopolymerization initiator containing the same 株式会社ADEKA 2024-12-03 CN disclosed
CN-112596338-B Colored resin composition, color filter using the same, and display device 住华科技股份有限公司 2024-11-26 CN disclosed
US-5939471-A COLLOIDAL SILICA DISPERSED IN RESIN MITSUBISHI RAYON CO., LTD. (JP) 1999-08-17 US disclosed
EP-0823450-A1 COMPOSITE AND MOLDINGS PRODUCED THEREFROM MITSUBISHI RAYON CO., LTD. (JP) 1998-02-11 EP disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US disclosed
US-5695851-A CROSSLINKABLE, POLYMERIZABLE COMPOSITION CONTAINING (METH)ACRYLOYLOXY GROUPS, SILICA WHOSE SURFACE HAS BEEN MODIFIED WITH AN ORGANOSILANE-CONTAINING COMPOUND, AND A HIGH ENERGY RADIATION POLYMERIZATION INITIATOR MITSUBISHI RAYON CO., LTD. (JP) 1997-12-09 US disclosed
EP-0696621-A1 COATING COMPOSITION AND SURFACE-COATED MOLDING PRODUCED THEREWITH MITSUBISHI RAYON CO., LTD. (JP) 1996-02-14 EP disclosed
US-4026826-A ALKOXYSILANES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-05-31 US disclosed