SCHEMBL5340912

SCHEMBL5340912

C/C=C(\C)[SiH2]OCC1CC2CCC1C2

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
KMT2A Q03164 1/20 0.32
MCHR1 Q99705 1/20 0.31
SCN9A Q15858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5338936 0.75
SCHEMBL5917732 0.72 MCHR1 (0.35) MEN1NPC1RAB9AKMT2AMCHR1
SCHEMBL5559403 0.71 ATM (0.39)
SCHEMBL13018439 0.69 MEN1 (0.35) MEN1NPC1RAB9AKMT2AMCHR1
SCHEMBL9517788 0.69 MEN1 (0.41) MEN1NPC1RAB9AKMT2ASCN9A
SCHEMBL13188783 0.69 MEN1 (0.40) MEN1NPC1RAB9AKMT2AMCHR1
SCHEMBL19055333 0.69 MCHR1 (0.37) MEN1NPC1RAB9AKMT2AMCHR1
SCHEMBL21466550 0.69 MCHR1 (0.37) MEN1NPC1RAB9AKMT2AMCHR1
SCHEMBL18379791 0.69 MCHR1 (0.37) MEN1NPC1RAB9AKMT2AMCHR1
SCHEMBL18714955 0.69 MCHR1 (0.37) MEN1NPC1RAB9AKMT2AMCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7220810-B2 Polymer film and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-22 US disclosed
US-7217830-B2 Organic silicon compound and method for preparing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-05-15 US disclosed
US-20060009600-A1 Polymer film and method for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-01-12 US disclosed
US-20060004219-A1 Organic silicon compound and method for preparing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004219-A1 Organic silicon compound and method for preparing the same AR, PKD1, SKP2 MEN1 68/4885NPC1 187/4885RAB9A 3232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.