Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.68 |
| ▸ | CTH | P32929 | 1/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.59 |
| ▸ | RRM2 | P31350 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RRM1 | P23921 | 1/20 | 0.59 |
| ▸ | RRM2B | Q7LG56 | 1/20 | 0.59 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL293101 | 1.00 | TOP2A (0.68) | TOP2ACTHADORA2AHKDC1RRM2 | |
| SCHEMBL31690655 | 0.86 | TOP2A (0.82) | TOP2ACTHADORA2AHKDC1NPC1 | |
| SCHEMBL28284810 | 0.85 | TOP2A (0.52) | TOP2ACTHADORA2AHKDC1RRM2 | |
| SCHEMBL31690665 | 0.84 | TOP2A (0.73) | TOP2ACTHADORA2AHKDC1NPC1 | |
| SCHEMBL13826730 | 0.83 | NPC1 (0.68) | TOP2ACTHNPC1RAB9AMEN1 | |
| SCHEMBL2562208 | 0.83 | TOP2A (0.68) | TOP2ACTHADORA2AHKDC1NPC1 | |
| SCHEMBL14542967 | 0.83 | NPC1 (0.59) | TOP2ACTHADORA2AHKDC1NPC1 | |
| SCHEMBL4100136 | 0.83 | NPC1 (0.59) | TOP2ACTHADORA2AHKDC1NPC1 | |
| SCHEMBL4100134 | 0.83 | NPC1 (0.59) | TOP2ACTHADORA2AHKDC1NPC1 | |
| SCHEMBL2562207 | 0.83 | TOP2A (0.68) | TOP2ACTHADORA2AHKDC1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 158 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184574-A | Modified polyoxometalate organic-inorganic hydrogel and preparation method and application thereof | 河南大学 | 2024-06-14 | — | — | CN | claimed |
| CN-110698511-B | Tin complex with 2-pyridinecarboxaldehyde thiosemicarbazone as ligand and synthesis method thereof | 广西师范大学 | 2021-09-14 | — | — | CN | claimed |
| US-20210229064-A1 | BRANCHED POLYMER CROSS-LINKED GRAPHENE OXIDE ADSORBENT MATERIAL | DUKE UNIVERSITY | 2021-07-29 | — | — | US | claimed |
| CN-109810128-B | Indium complex with 2-pyridylaldehyde thiosemicarbazone as ligand and synthetic method and application thereof | 广西师范大学 | 2021-04-02 | — | — | CN | claimed |
| CN-112079853-A | Zinc complex with 2-pyridylaldehyde thiosemicarbazone as ligand and synthetic method and application thereof | 广西师范大学 | 2020-12-15 | — | — | CN | claimed |
| CN-110698511-A | Tin complex with 2-pyridinecarboxaldehyde thiosemicarbazone as ligand and synthesis method thereof | 广西师范大学 | 2020-01-17 | — | — | CN | claimed |
| CN-109897071-A | It is a kind of using 2- pyridine carboxaldehyde thiosemicarbazones as the platinum complex of ligand and its synthetic method and application | 广西师范大学 | 2019-06-18 | — | — | CN | claimed |
| CN-109810128-A | It is a kind of using 2- pyridine carboxaldehyde thiosemicarbazones as the indium complex of ligand and its synthetic method and application | 广西师范大学 | 2019-05-28 | — | — | CN | claimed |
| CN-106630200-A | Scale inhibitor and preparation method therefore and scale inhibiting method of seawater desalting device | 国家开发投资公司 | 2017-05-10 | — | — | CN | claimed |
| CN-102060866-B | Rare earth ternary complex as well as preparation method and application thereof | UNIV SHANGHAI | 2013-01-16 | — | — | CN | claimed |
| CN-102417516-A | 2-pyridylaldehyde thiosemicarbazone Schiff base/8-hydroxyquinoline/rare earth ternary complex, and preparation method and application thereof | UNIV SHANGHAI | 2012-04-18 | — | — | CN | claimed |
| CN-102060866-A | Rare earth ternary complex as well as preparation method and application thereof | UNIV SHANGHAI | 2011-05-18 | — | — | CN | claimed |
| US-7521062-B2 | Thiosemicarbazones as anti-virals and immunopotentiators | NOVARTIS VACCINES & DIAGNOSTICS, INC. (US) | 2009-04-21 | — | — | US | claimed |
| US-4655885-A | DIRECTLY TRANSFERRING ELECTRONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-04-07 | — | — | US | claimed |
| EP-0187719-A2 | Surface-modified electrode and its use in a bioelectrochemical process | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-07-16 | — | — | EP | claimed |
| JP-6128230-A | — | — | None | — | — | JP | disclosed |
| US-12144833-B1 | Copper chelation therapeutics | BERMUDES DAVID GORDON (US) | 2024-11-19 | — | — | US | disclosed |
| US-4657903-A | Transition metal complexes of the selenium analogs of 2-acetyl- and 2-propionylpyridine thiosemicarbazones useful for treating malarial infections and leukemia | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1987-04-14 | — | — | US | disclosed |
| US-4655885-A | DIRECTLY TRANSFERRING ELECTRONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1987-04-07 | — | — | US | disclosed |
| EP-0187719-A2 | Surface-modified electrode and its use in a bioelectrochemical process | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-07-16 | — | — | EP | disclosed |