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SCHEMBL534323

SCHEMBL534323

CC(C)(C)OC(=O)N(C(=O)c1cccc(C(N)(Cc2ccc(-c3ccccc3)cc2)S(=O)(=O)c2cccnc2)n1)C(C(=O)O)C(C)(C)C

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ PTGER2 P43116 15/20 0.37
▸ ADAMTS4 O75173 1/20 0.36
▸ F2 P00734 1/20 0.32
▸ CTPS1 P17812 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL533798 0.93 PTGER2 (0.33) PTGER2F2
SCHEMBL534324 0.86 PTGER2 (0.38) PTGER2ADAMTS4
SCHEMBL3458705 0.85 PTGER2 (0.40) PTGER2
SCHEMBL534169 0.81 PTGER2 (0.40) PTGER2ADAMTS4
SCHEMBL533712 0.81 PTGER2 (0.40) PTGER2ADAMTS4
SCHEMBL11023982 0.81 PTGER2 (0.58) PTGER2
SCHEMBL533599 0.80 PTGER2 (0.42) PTGER2ADAMTS4
SCHEMBL11021481 0.80 PTGER2 (0.41) PTGER2ADAMTS4
SCHEMBL17472613 0.80 PTGER2 (0.47) PTGER2ADAMTS4F2CTPS1
SCHEMBL3458709 0.79 PTGER2 (0.41) PTGER2F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8648097-B2 Pyridylaminoacetic acid compound UBE INDUSTRIES, LTD. (JP) 2014-02-11 — — US disclosed
EP-2415763-A1 PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA Ube Industries, Ltd. (JP) 2012-02-08 — — EP disclosed