Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.57 |
| ▸ | CTSD | P07339 | 9/20 | 0.57 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613442 | 0.87 | BACE1 (0.60) | BACE1CTSDBACE2 | |
| SCHEMBL3905750 | 0.86 | BACE1 (0.62) | BACE1CTSDBACE2 | |
| SCHEMBL3915537 | 0.86 | BACE1 (0.64) | BACE1CTSDBACE2 | |
| SCHEMBL3905817 | 0.86 | BACE1 (0.61) | BACE1CTSDBACE2 | |
| SCHEMBL3349752 | 0.86 | BACE1 (0.60) | BACE1CTSDBACE2 | |
| SCHEMBL3350763 | 0.85 | BACE1 (0.59) | BACE1CTSDBACE2 | |
| SCHEMBL3912895 | 0.85 | BACE1 (0.58) | BACE1CTSDBACE2 | |
| SCHEMBL3913841 | 0.85 | BACE1 (0.58) | BACE1CTSDBACE2 | |
| SCHEMBL3352764 | 0.84 | BACE1 (0.59) | BACE1CTSDBACE2 | |
| SCHEMBL3357620 | 0.84 | BACE1 (0.57) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214715-B2 | Compounds to treat Alzheimer's disease | PHARMACIA & UPJOHN (US) | 2007-05-08 | — | — | US | disclosed |