Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | USP8 | P40818 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6516006 | 0.89 | PTGER2 (0.32) | ADAM17USP2USP8SLC1A3SLC1A2 | |
| SCHEMBL533750 | 0.82 | USP2 (0.31) | ADAM17USP2USP8 | |
| SCHEMBL11021873 | 0.81 | PTGER2 (0.40) | — | |
| SCHEMBL533748 | 0.80 | SLC1A3 (0.32) | ADAM17SLC1A3SLC1A2SLC1A1ITGAV | |
| SCHEMBL534421 | 0.78 | SLC1A3 (0.31) | ADAM17SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3458629 | 0.78 | F2 (0.31) | ADAM17USP2USP8SLC1A3SLC1A2 | |
| SCHEMBL6516015 | 0.77 | PTGER2 (0.31) | SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL533428 | 0.70 | SLC1A3 (0.33) | ADAM17USP2USP8SLC1A3SLC1A2 | |
| SCHEMBL3458635 | 0.70 | PTGER2 (0.33) | — | |
| SCHEMBL15647720 | 0.70 | PTGER2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415763-B1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | UBE INDUSTRIES (JP) | 2016-01-27 | — | — | EP | disclosed |
| US-8648097-B2 | Pyridylaminoacetic acid compound | UBE INDUSTRIES, LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| EP-2415763-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING GLAUCOMA | Ube Industries, Ltd. (JP) | 2012-02-08 | — | — | EP | disclosed |